Computational Biochemistry: Systems Biology Minireview Series*
نویسندگان
چکیده
منابع مشابه
Chemical biology meets biological chemistry minireview series.
What is the difference between “biological chemistry” and “chemical biology?” One of us (J. M. G.) received his Ph.D. at an institution where the biochemistry building was called the Laboratory of Chemical Biology, but that was a long time ago, and things have changed. Biological chemistry (or biochemistry), that is the study of life processes at the molecular level, is now quite distinct from ...
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It is estimated that one-third of all proteins are integral membrane proteins, defined narrowly as proteins that completely traverse the membrane bilayer. There also exists a smaller but unknown number of monotopic membrane proteins, including prostaglandin endoperoxide H synthases, that interdigitate into a single leaflet of the lipid bilayer via a specific membrane binding domain (1). Additio...
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Metals are present in nearly one-half of protein structures analyzed to date and play important roles in many of these enzymes. This prologue introduces the third of the Thematic Minireview Series on Metals in Biology, which is focused on iron homeostasis. The four minireviews in the current series deal with redox cycling in iron metabolism, the biogenesis and assembly of iron-sulfur centers (t...
متن کاملIntroduction to Minireview Series: “Chemical Biology Meets Biological Chemistry”
What’s the difference between “biological chemistry” and “chemical biology”? One of us (JMG) received his Ph.D. at an institution where the biochemistry building was called the Laboratory of Chemical Biology, but that was a long time ago and things have changed. Biological chemistry (or biochemistry), that is the study of life processes at the molecular level, is now quite distinct from chemica...
متن کاملComputational Systems Biology
The complex biological systems consist of distinct molecules that exert their functions by interacting with each other, which makes it a big challenge to understand how the cellular machinery works. Recently, the accumulation of a large amount of multiscale omics data, such as nextgeneration sequencing data and protein interaction data, provides opportunity to investigate the functions of molec...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2009
ISSN: 0021-9258
DOI: 10.1074/jbc.r800066200